You gotta love this structure

Science vol. 352 pp. 1555 – 1559 has a structure you have to love. It is a molecular knot containing a mere 30 pyridines and 10 benzenes all tied together in a knot which looks like a five pointed star. The tying was done by metathesis of benzenes with CH2 CH2 CH = CH2 dangling from them. To think of what needed to be tied to what was extremely clever.

Surprisingly with all this going on the knot coordinates just a single halogen atom. This shows why you must build a model of a complicated organic compound to see what it really looks like, something I learned with adamantane years ago — you can draw all the chairs you want, making it look rather spiky, but the damn thing is actually spherical. Well, no model was built, but the structure was determined using Xray crystallography (figure 3) Anyone playing with tinkertoys back in the day (or Legos now) and loving it will have a natural affinity for organic chemistry

Post a comment or leave a trackback: Trackback URL.


  • John wayne  On June 30, 2016 at 10:14 am

    The other day my mom asked me why I’m good at what I do. I told her it is a combination of being able to understand the complicated (Dungeons and Dragons) combined with being able to intuit things in three dimensions (Legos, mostly Star Wars these days – I had Lincoln Logs too).

  • chemdiary  On June 30, 2016 at 10:54 am

    I don’t understand why this paper made it into Science. Nothing extraordinary here.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

%d bloggers like this: